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In patients with MG, the number of AChRs at the NMJ is low, which results in a decreased number of interactions between ACh and its receptor.

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As a result, there is less acetylcholine signaling from nerve to muscle, leading to symptoms of muscle weakness.

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Some medications used to treat MG, like Prednisone, can lead to problems with memory.

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ME patients showed extreme deficiency of acetylcholine levels, which can affect the performance of the vagus nerve, but can also affect the central nervous system (brain).

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